Pharmacology of Anticoagulants

Objectives

Discuss various different antithrombotic agents or anticoagulants

Describe the MoA of heparin and LMWH, warfarin, ticlopidine, lopidogrel, danaparoid, hirudin, fondaparinux, dabigatran, rivaroxabn, apixaban, argatroban, streptokinase, and tissue plaminogen activator

platelets.jpg 600px-Coagulation_full.png

heparin and LMWH
warfarin
ticlopidine, clopidogrel
danaparoid
hirudin
fondaparinux
dabigatran
rivaroxabn, apixaban
argatroban
streptokinase, and tPA

Describe the differences between standard heparin and LMWH

List the possible common side-effects and complications of antithrombotic drugs

List the antidotes to various drugs

Heparin
Warfarin

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