RBC Indices and Abnormalities

Describe the normal steps of RBC production in the bone marrow, major sequence of maturation, and which forms are released into the peripheral blood

List the normal RBC indices (number, size, shape, and hemoglobin [Hb] content)

Define reticulocytes and explain their significance in the peripheral blood

List common RBC abnormalities: number, size, shape, colour, hemoglobin content, cell membrane disorders, and inclusions

List 3 most common factors that may give false low or high hemoglobin [Hb] value

Give examples [congenital and acquired] associated with RBC abnormalities

  • Sickle cell disease
  • Thalassemia


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