Normal and Benign White Blood Cell Disorders

Objectives

List the different subtypes of white blood cells seen in peripheral blood under normal conditions. Define morphological and functional features of each cell subtype

Subtype Morphological Features Functional Features

Define: Leukocytosis, leukopenia (or leukocytopenia)

Leukocytosis
definition
Leukopenia
def

List most common causes for leukocytosis and leukopenia

Leukocytosis

  • definition

Leukopenia

  • def

Describe the morphological changes seen in neutrophils in bacterial infections

Explain the pathogenesis of: toxic granules, toxic vacuoles, and Döhle bodies

toxic granules:

toxic vacuoles:

Döhle bodies

Identify the defect present in "chronic granulomatous disease"

Identify the major WBCs dysfunction in Chediak‐Higashi syndrome


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